Chemistry and Structure-Activity Relationship of Antibacterial Nucleoside Natural Products
نویسندگان
چکیده
منابع مشابه
Structure activity relationship study of Mezzettiasides natural products and their four new disaccharide analogues for anticancer/antibacterial activity.
Ten members of the mezzettiaside family of natural products were synthesized and evaluated for anticancer and antibacterial activity. Complete anticancer (H460) and antibacterial (B. subtilis) activities for the ten natural products and four new analogues were found. Comparison to the cleistrioside and cleistetroside classes of natural products were made.
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This Special Issue of Molecules deals with the structure–activity relationship of natural compounds which possess some pharmacological/chemical properties of potential interest (from basic research to the clinical applications) in a wide range of areas, such as bacteriology, parasitology, cancerology, inflammation, etc. The molecules that have been studied in the eleven published articles of th...
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Mammalian ingestion of jervane, solanidane, and spirosolane steroidal alkaloids produces craniofacial congenital malformations in offspring upon administration during the primitive s t rdneura l plate developmental phase. Structure-terata studies have shown that hamster teratogenicity induced by steroidal alkaloids is primarily related to the presence of C-5, C-6 unsaturation and secondarily to...
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ژورنال
عنوان ژورنال: Nucleic Acids Symposium Series
سال: 2008
ISSN: 0261-3166,1746-8272
DOI: 10.1093/nass/nrn039